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Odyne (Flutamide)

Odyne is an oral antiandrogen: it has been licensed in Italy, the USA, the UK, and other countries for prostate cancer only. However, the drug is often prescribed for acne, hirsutism, and alopecia in women with polycystic ovarian syndrome. In the course of our work as forensic doctors investigating medical malpractice, one case of fulminating and lethal hepatitis in a woman treated with Odyne for acne and hirsutism was brought to our attention.

Other names for this medication:
Flutamide, Eulexin, Andraxan, Drogenil, Etaconil, Flutamida, Flutan, Ftda, Fugerel, Odyne, Prostamide, Prostandril, Tafenil,

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Odyne is used together with a luteinizing hormone-releasing hormone (LHRH) agonist to treat metastatic (cancer that has spread) prostate cancer in men. Odyne belongs to the group of medicines called antiandrogens. It works by blocking the effects of androgen (a male hormone), to stop the growth and spread of cancer cells.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Capsule

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Additionally, the results show that the tumor-specific TsF1 raised in one suppressor system share serologic determinants with anti-hapten TsF1 raised in another. Improved cardiac performance by salbutamol, a selective beta 2-agonist, in chronic cor pulmonale.

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Inter-ocular transfer of stimulus cueing in dominance selection at the onset of binocular rivalry. In postpartum haemorrhage (PPH), as for other causes of acute haemorrhage, management can have a major impact on patient outcomes. (2) The expression of p-STAT3 (Ser) was activated at 30 min and remained at a high level until 4 h. and Tagetes terniflora Kunth against winged and wingless adults of Metopolophium dirhodum (Walk.). Despite overall structural similarity, recombinant forms of the Ace and Cna ligand-binding domains exhibit significantly different affinities and binding kinetics for collagen type I (CI) in vitro.

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Current diagnostic tools applied at clinics have had very limited success in early detection. The magnitude of enhanced transcription can fully account for the increase in the mRNA.

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Long-term outcome in kidney transplant recipients over 70 years in the Eurotransplant Senior Kidney Transplant Program: a single center experience. Adaptor-dependent degradation of a cell-cycle regulator uses a unique substrate architecture.

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Blunt snout bream (Megalobrama amblycephala) is an herbivorous freshwater fish species native to China and has been recognized as a main aquaculture species in the Chinese freshwater polyculture system with high economic value. The five trk genes are differentially expressed in the developing brain, spinal cord, cranial ganglia, and retina. Plant promoter architecture is important for understanding regulation and evolution of the promoters, but our current knowledge about plant promoter structure, especially with respect to the core promoter, is insufficient. A systems biology approach was used and differentially expressed transcripts as well as regulatory interactions were identified.

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This article undertakes a comprehensive review of the three kinds of evidence that have been most prominent in recent discussion: studies of retrograde amnesia in memory-impaired patients who have well-characterized lesions, neuroimaging of healthy volunteers, and work with experimental animals including lesion studies, imaging and mouse genetics. Although skin grafting has been commonly performed, stenosis, infection and delayed wound healing often occur postoperatively. Microscopical observations roughly confirmed, that living keratinocytes and inner stratum corneum are the main sites of free thiol groups, while disulphide crosslinks are almost exclusively found in cornified cells.

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To evaluate the risk factors for overactive bladder (OAB) in a population aged 40 years and over in the community. Biliary tract cancers (BTC) are a relatively rare heterogeneous group of four to five anatomically distinct cancers whose prognosis is poor, even in the setting of attempted curative resection. The change of cell death was determined by Tyrpan blue staining assays. Epigenetics: are there implications for personalised nutrition? The widely used (His)(6)-tag shows affinity for bivalent ions such as nickel or cobalt, which can on their turn be easily coated on magnetic beads.

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In critically ill patients with acute congestive HF acute renal impairment function and the modulation of NOS determine plasma ADMA/SDMA levels after therapy. Once-daily tacrolimus extended-release formulation: 1 year after conversion in stable pediatric kidney transplant recipients. Location of T cell and major histocompatibility complex antigens in the human thymus. All subjects who were positive for EMA were advised to undergo an intestinal biopsy and HLA typing. Registrants reporting post September 11th onset of a lower respiratory symptom in the first survey and the same symptom in the second survey were solicited as potential cases.

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Activation of natural killer cells in vitro by a product of beta-hemolytic streptococci. The extensor digitorum, extensor indicis and extensor digiti minimi tendons displayed a variant pattern.

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Automatic triggers built into an EHR can help physicians identify such patients and establish medical necessity for services that both improve patient care and increase revenue for the organization. Current literature supports a role for MSCs in modulating heterotopic bone formation, and direct manipulation of MSCs might one day be used to prevent and treat HO.

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Thus, changes in cell-surface carbohydrates during malignant development in the rat palate seem to follow closely the histomorphological changes. The method by Nagatsu and Udenfriend (1972) to measure dopamine-beta-hydroxylase (DBH) activity was applied for tissue samples. We conducted a retrospective study of patients initiating injectable antimicrobials for MDR-TB treatment in five UK centres between January 2004 and December 2009. A semi-structured questionnaire was administered to 400 randomly selected patients aged 15 to 45 years visiting Kathmandu Model Hospital from May to July 2011, seeking any awareness of FAS, knowledge of its impact on fetal development and knowledge of the appropriate time of supplementation. Here, we show that Pro-boropro a potent inhibitor of DPP activity has a costimulating effect in hematopoietic colony assays for macrophage and, to a lesser extent, for granulocyte colonies and has a stimulating effect in organ cultures of immature thymocytes.

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Double-blind, placebo-controlled, crossover trial of inositol treatment for panic disorder. TimeTree2 interprets complex and hierarchical data from these studies for each user query, which can be launched using an iPhone application, in addition to the website. The method is based on the scission of an aptamer into two probes, which are then attached with a chemically reactive fluorogenic compound.

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Hypothesis on the nature of comprehension deficit in a patient with transcortical mixed aphasia with preserved naming. Electrophysiological manifestations of the excitable gap of slow-fast AV nodal reentrant tachycardia demonstrated by single extrastimulation. Fractionalization noise in edge channels of integer quantum Hall states.

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This study investigated the color parameters, tannin concentrations and tannin composition of a 50 year series of Cabernet Sauvignon wines from a commercial label as well as 30 year series of Cabernet Sauvignon and Shiraz wines from a separate commercial label to assess the impact of wine age on phenolic composition and concentration. Lansoprazole increased HO-1 mRNA levels in endothelial cells and HO-1 protein levels in macrophages. During the 1990s, application of molecular biology to the study of inherited drug-related phenotypes proved the genetic basis of several genetic polymorphisms. Histamine regulates relevant murine dendritic cell functions via H4 receptor. Perturbation of hyaluronan synthesis in the trabecular meshwork and the effects on outflow facility.

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The frequency of mammary tumors was significantly lower in ovariectomized vs sexually intact rats (2/47 vs 24/49), as was the frequency of pituitary adenomas (2/46 vs 27/41). Surface ultrastructure of cultures of affected psoriatic keratinocytes, unaffected psoriatic keratinocytes and normal keratinocytes. However, the length of protection afforded by UV-irradiated L3 was substantially greater than that resulting from immunization with non-irradiated L3.

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At low FTOH concentration levels, mass transfer and uptake was best for short-chain FTOH. Although peripartum cardiomyopathy (PPCM) is a rare disease, it has very serious consequences for both mother and child.

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Separation of blood cells from normal blood and blood of patients with various malignant blood diseases using separation media. The high rates of depression and anxiety reinforced the need for recognition and treatment of mental disorders in epilepsy. Metabolism of methotrexate and gamma-tert-butyl methotrexate by human leukemic cells in culture and by hepatic aldehyde oxidase in vitro. Mechanisms responsible for onset and development of these destructive processes during ontogeny are discussed.

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A hypothesis is advanced that the long recovery time of INa is one of the mechanisms providing long pharmacological action of quaternary antiarrhythmic and local anesthetic ammonium compounds. Solution structure of the LIM-homeodomain transcription factor complex Lhx3/Ldb1 and the effects of a pituitary mutation on key Lhx3 interactions. We sampled the intertidal rocky shore mussel Perna perna in a South African bay and along the nearby open coast, and sequenced maternally-inherited mtDNA (there is no evidence for paternally-inherited mtDNA in this species) and a biparentally-inherited marker. Enhancing relationships and improving communication between providers. Transcription factor specification codes defining distinct histogenetic domains within this grid are evolutionarily conserved across vertebrates and may reflect an underlying common vertebrate bauplan.

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Cancerous inhibitor of protein phosphatase 2A (CIP2A) is highly expressed in hepatocellular carcinoma (HCC) and promotes cell proliferation, cell invasion, and aggressive tumor behavior. F(1) hybrids were readily produced, and on average, the success of crosses producing subsequent generations (F(2), BC) decreased (though remained substantial), but the success of crosses was highly dependent on the genotypes involved. VARIANT: Command Line, Web service and Web interface for fast and accurate functional characterization of variants found by Next-Generation Sequencing. In this regime, F8H5PC molecules reach maximal compaction and display the highest apparent interfacial elasticity.

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In this study, we analyzed the expression of four chromosome 1-related genes, namely c-Jun, p73, Casp-9 and N-ras, in 60 cases of thymic epithelial tumors. The development of pulmonary hypertension in COPD adversely affects survival and exercise capacity and is associated with an increased risk of severe acute exacerbations.

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Maximizing detergent stability and functional expression of a GPCR by exhaustive recombination and evolution. The very low birthweight infant: maternal complications leading to preterm birth, placental lesions, and intrauterine growth. The group that was positive for cathepsin L expression tended to have positive metastatic neck lymph nodes and a poorer prognosis.

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Primary extramedullary plasmacytomas of the eyelid are rare with only five other cases reported in the literature. The pyramidal cells of layer V of the temporal cortex were heavily labeled ipsilaterally. Fifteen patients with recurrent gynecologic cancer (12 ovarian, 1 fallopian tube, 1 endometrial and 1 cervical cancer) who had experienced a hypersensitivity reaction to carboplatin and a possible clinical indication for continuing treatment with platinum were treated with nedaplatin (80 mg/m(2) )-containing regimen. Both human and laboratory animal cytochrome P450s (CYPs) were able to oxidize Sudan I, whereas Sudan III modified CYP activities. The remaining 17 PDIs could also be adapted for claims data to assess the quality of pediatric care.

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Current status of hepatocellular carcinoma treatment in Japan: transarterial chemoembolization. Hair transplants for male pattern baldness--special clinical and mathematical considerations. The study revealed that during 8 months of Herbst therapy there was a significant increase in mandibular length, along with sagittal repositioning. Motorized vibrating manure forks were used in beach-cleaning operations following the massive Deepwater Horizon oil spill in the Gulf of Mexico during the summer of 2010.

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IL-4 suppresses very late antigen-4 expression which is required for therapeutic Th1 T-cell trafficking into tumors. Enhanced protein synthesis in a cell-free system from hypertrophied skeletal muscle. Patients with serum phosphate levels greater than 5.5 mg/dL during the washout period were included for treatment with oAC. The modern management of splenic injury: a model for coordinated trauma services.

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Sudden death during worker transportation due to massive pulmonary thromboembolism: a case report. The clinical factors including pathological data reviewed by a central pathologist and follow-up data were prospectively collected. Biochemical analysis of the complex between the tetrameric export adapter protein Rec of HERV-K/HML-2 and the responsive RNA element RcRE pck30. Immune tolerance induction (ITI) is the only therapeutic approach that can eradicate factor VIII (FVIII) inhibitors in patients with hemophilia A.

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The prevalence estimates were summarized through a systematic review and meta-analysis of published literatures. (2) When penicillinase was applied simultaneously with penicillin, the fully developed epicortical FIED were accompanied by negative intracortical field potentials which in this case reached a depth of 900 micrometers. The primary objective of this paper is to introduce a novel working hypothesis with respect to the endogenous source of this compound in humans: the idea that muscle tissue acts as an extrahepatic production site of substantial amounts of isoprene. In the scientific literature, we found numerous pharmacogenomic and pharmacogenetic biomarkers concerning 43 of the 109 anticancer agents.

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We used estimates from the 2005 Canadian Community Health Survey to study residents who were aged 45 years or older and from the lowest income quintile nationally. Infection with hepatitis viruses following blood exposure accidents, such as needle stick injuries, is a serious issue for medical staff. However, prolonged treatment frequently involves adverse side effects.

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All subjects were interviewed using the symptom checklist Examination of Anomalous Self-Experience. The number of involved joints correlated with levels of ESR, SAA and CRP. Functional studies of the protease, proprotein convertase (PC)6, the gp130 cytokines, leukemia inhibitory factor (LIF) and interleukin (IL)11 and the chemokines, CX3CL1 and CCL14 demonstrate potential actions within the uterine cavity. However, the quantitative knowledge of evolution of three-dimensional (3D) trabecular microstructure in adaptation to the external forces is currently limited. Dimorphic allele segments, termed C-fragment and F-fragment, have been found in high endemicity malaria areas and associations between the dimorphism and severe malaria have been described.

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Dynamic empirical data, derived from quail embryos, show that vascular beds readily form within a moving extracellular matrix (ECM) microenvironment-which we analogize to the de novo vascularization of small rapidly growing tumors. Particularly significant was the fact that the bactericidal activity was mainly associated with the population of antibodies that did not crossreact with the GBMP. A silicone-based controlled-release device for accelerated proteolytic debridement of wounds. In response to symptoms ascribed to air quality problems, it may be appropriate to address employee perceptions regarding the work environment in addition to evaluating environmental characteristics relating to chemicals, biological contamination, air movement, temperature, and humidity. Material mismatch causes stress concentrations at the interfaces.

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Detection of RNA transcripts in normal lymphoid and myeloid colonies. Quantitative analysis of segmental deformation by SENC and STE allowed accurate distinction of myocardial segments with different functional states. Epidemiologic and diagnostic aspects of bacteriuria: a longitudinal study in older women. To evaluate the safety and efficacy of orally administered ruboxistaurin (RBX) as a mesylate salt in patients with diabetic macular edema (DME). The translational failure with neuroprotective drugs has forced us to look for alternative approaches.

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In the efficacy meta-analysis, a greater number of infliximab-treated patients relative to those in the placebo group achieved ACR20, ACR50, and ACR70 values from 14 weeks to 2 years of treatment. Taken together, one may conclude that processes of cross-modal spatial adaptation, but not those of compensatory plasticity, occurred in patients with hemianopia. The design and construction of a novel apparatus to fire polish patch-clamp recording pipets is described. Resynchronization therapy for right ventricular failure: restoring harmony in left ventricular contractility. Comparison to the theoretical proteome revealed an underrepresentation of membrane proteins, though the identified proteins cover all predicted subcellular localizations and all functional classes.

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BRCT domains are predominantly found in proteins involved in cell cycle control and DNA repair. The present study demonstrates the ability of the interaction potential model to well describe most ice structures found in the phase diagram of water and to estimate the relative stability of 16 known phases through a cluster analysis of simulated powder diagrams of polymorphs obtained from MD simulations.

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Preparation of uniform-sized agarose beads by microporous membrane emulsification technique. Habitat suitability mapping of Anopheles darlingi in the surroundings of the Manso hydropower plant reservoir, Mato Grosso, Central Brazil.

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An interaction between DNA polymerase and helicase is essential for the high processivity of the bacteriophage T7 replisome. The present paper provides an overview of current clinical knowledge on the role of adhesive molecules and cytokines in endothelial dysfunction and overt atherosclerosis. Schizanthus (Solanaceae) has zygomorphic flowers and consists of 12 species of annual or biennial herbs that are distributed mainly in Chile and characterized by bee-, hummingbird-, and moth-pollination syndromes. The latter two groups correspond to medial lamina VII group of the lumbar to the caudal segments and the ventral horn group of the sacral-caudal segments of our previous studies.

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The proposed method is examined by an experimental study using three MCDM methods, the well-known clustering algorithm--k-means, ten relative measures, and fifteen public-domain UCI machine learning data sets. Characteristics of high-frequency consumers of prescription psychoactive drugs. Three new anthracene derivatives, 2,6-bis(4-decylphenyl)anthracene (DDPAnt), 2-decyl-5-(2-(5-decylthiophen-2-yl)anthracen-6-yl)thiophene (DDTAnt), and 2,6-bis(4-decyloxy phenyl) anthracene (DDPXAnt) were synthesized by Suzuki cross-coupling reaction. Propranolol reduces infantile hemangioma volume and vessel density. Two Palmaz stents were used to form the veno-venous reanastomosis.

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The expression pattern of the c-src gene product in the melanomas tested was differential and varying kinase levels in different metastases from the same patient were detected. Longer overall survival in a patient with advanced non-small cell lung cancer treated with Chinese medicine and chemotherapy. Management of choledocholithiasis and its complications is variable and often requires transfer to a specialty facility. This case exemplifies that knowledge of nervous anatomy and physiology is the basis of the semiology of the nervous system.

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No significant differences in the binding of IFN were found between short-and long-term IFN treated cells. Six adult male Sprague-Dawley rats were flown on the 7-day US space shuttle mission STS-54. RMS measurements of amplitude symmetry were calculated for samples of typical active and quiet sleep periods in 12 normal full term, 5 premature and 7 Trisomy-21 infants from recordings obtained at 1, 4, 12 26 and 52 weeks post term.

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Psychological and physiological dependence in smokers and there effect on motivation for smoking cessation After an introductory lecture and demonstration, each student was allowed three attempts to intubate using each method in random order.

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In single crystals of 2H-NbSe2, we identify for the first dapoxetina generico argentina time a crossover from a weak collective to a strong pinning regime in the vortex state which is not associated with the peak effect phenomenon. The affinity to each patch may differ, and the relative specificity to each synapse may ensue. Despite the entry of food allergens via the intestinal tract, in the majority of dogs with AFR, clinical symptoms are only associated with the skin (CAFR).

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Specifically, deregulation of the process of translation initiation appears to play a key role in oncogenesis. Inbred female Lewis rats were exposed to cigarette smoke tibolone tablets india for 6 mo and then received BMCs, MSCs, or MSC-CM from male Lewis rats. The BXD recombinant inbred panel is a very well characterized genetic reference panel which allows quantitative trait locus (QTL) analysis of miRNA abundance and detection of correlates in a large store of brain and behavioural phenotypes. Anesthetics and automaticity of dominant and latent pacemakers in chronically instrumented dogs. The lack of OPG in HVSMCs or treatment with RANKL or TRAIL did not affect proliferation of HVSMCs.

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A selective temperature program proved to be the decisive factor in separating the various methylated anticonvulsants. Transfer of data and knowledge important for clinical decision-making without language barriers is demonstrated on features of the European Journal for Biomedical Informatics. bactrim ds generic picture HRV was measured during dissection around the recurrent laryngeal nerve.

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It is often assumed that the efficiency of selection for mutational robustness would be proportional to mutation rate and population size, thus being inefficient in small populations. Conformational sampling of CYP3A4 with molecular dynamics simulations along multiple trajectories were used to generate representative structures for docking studies using recently published heme parameters. This paper presents a new method to difference between omeprazole tablets capsules and pills measure C based on analysis of the phase signal of SMI signals in the frequency domain.

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Effect of cognitive load on eye-target synchronization during smooth pursuit eye movement. Staining was observed only in the epithelial cells of the thymomas olmesartan medoxomil amlodipine hydrochlorothiazide tablets side and thymic hyperplasia and correlated well with electron microscopic studies. In the present communication, we studied the effect of curcumin on matrix-metalloproteinase-2 (MMP-2), integrin receptors, and focal adhesion kinase (FAK) in human laryngeal cancer cells, HEp2.

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Changing the medium to serum-free medium of confluent epithelial cells induced a complete proliferative response which started with a transient increase in c-fos and c-myc mRNA, followed by the expression of max. What the emergency radiologist needs to know about treatment-related complications from conventional chemotherapy and newer molecular targeted agents. To our knowledge, these celecoxib side effects dosage for benadryl two cases with biphasic malignant mesothelioma and osseous differentiation with long survival are the first to be described from Central Anatolia.

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CCl4 has induced cirrhosis from 36 hours to 18 weeks after injection and BDL from seven days virex p suspension to four weeks after surgery. All patients presented characteristic history and results of performed diagnostic tests. There is considerable variation across SSA in the use and acceptance of NPCS. Case study: Risks associated with congenital varicella infection.

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We examined the associations of English proficiency with type-2 diabetes (T2DM) and diabetic retinopathy (DR) in Asian Indians living in Singapore, an urban city where English is the predominant language of communication. Cryopreservation of epididymal bovine spermatozoa from dead animals and its uses in vitro embryo production. The in vivo effect of FTY720 was evaluated using a murine zenograft model. At a shorter 200 ms CTOA, the spatial effect becomes stronger while the temporal cost is replaced by a antibiotic metronidazole adalah ialah temporal benefit. OpenEHR-based representation of guideline compliance data through the example of stroke clinical practice guidelines.