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Apcalis (Tadalafil)
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Tadalafil

Apcalis (Apcalis) and Viagra (sildenafil) are oral drugs that are used for treating impotence (the inability to attain or maintain a penile erection) and benign prostatic hyperplasia (BPH). They are in a class of drugs called phosphodiesterase-5 (PDE5) inhibitors that also includes vardenafil (Levitra, Staxyn ODT), and avanafil (Stendra). Penile erection is caused by the engorgement of the penis with blood. Under normal conditions, sexual stimulation leads to the production and release of nitric oxide in the penis. Nitric oxide then activates the enzyme, guanylate cyclase, which causes the production of cyclic guanosine monophosphate (cGMP). It is the cGMP that is primarily responsible for the erection by affecting the amount of blood that the blood vessels deliver and remove from the penis. Apcalis and Viagra inhibit an enzyme called phosphodiesterase-5 (PDE5) which destroys the cGMP. Thus, Apcalis and Viagra prevent the destruction of cGMP and allows cGMP to accumulate and persist longer. The longer cGMP persists, the more prolonged the engorgement of the penis.

Other names for this medication:
Tadalafil, Adcirca, Apcalis, Cialis, Femalefil, Forzest, Ladialis, Snafi, Tadacip, Tadalafilo, Tadalis, Tadalista, Tadora, Vidalista, Zydalis,

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Secalip, Irfen, Valcivir, Pepzol, Azitrocin, Alep, Hydrochlorothiazide, Efac, Gabator, Dicloduo, Nizagara, Amixen, Fulvicin, Regonol, Zyllt, Orten, Barambo, Clipto, Zovanta, Calutide, Vensir, Dorover, Balkatrin, Penmox, Lanzol, Prolifen, Rulid, Tryptanol, Zoltar, Ozidia,

Apcalis comes as a tablet to take by mouth. It may be taken with or without food.

If you are taking Apcalis to treat erectile dysfunction, follow your doctor's directions and the guidelines in this paragraph. There are two different ways to take Apcalis, either daily or on an as needed basis. Talk to your doctor about which dosing schedule is right for you. Apcalis is sometimes taken as needed, usually at least 30 minutes before sexual activity and not more often than once every 24 hours. Your doctor will help you decide the best time for you to take Apcalis before sexual activity. Apcalis is also sometimes taken once a day every day without regard to timing of sexual activity. You may attempt sexual activity at any time between doses. If you are taking Apcalis on a regular schedule, take it at around the same time every day. If you have certain health conditions or are taking certain medications, your doctor may tell you to take Apcalis less often or may prescribe a lower dose to be taken once a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Apcalis exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

If you are taking Apcalis to treat PAH or BPH, follow your doctor's directions and the guidelines in this paragraph. You should take Apcalis one time a day. Take all of the tablets for your daily dose at one time each day; do not divide the tablets to take as separate doses. Take Apcalis at around the same time every day. If you are already taking medication to treat BPH, your doctor may tell you to stop taking your other medication at least one day before starting treatment with Apcalis. Follow your doctor's directions carefully, and ask your doctor or pharmacist to explain any part you do not understand.

If you are taking Apcalis for erectile dysfunction, your doctor will probably start you on an average dose of Apcalis and increase or decrease your dose depending on your response to the medication. Tell your doctor if Apcalis is not working well or if you are experiencing side effects.

If you are taking Apcalis for PAH, you should know that Apcalis controls PAH but does not cure it. Continue to take Apcalis even if you feel well. Do not stop taking Apcalis without talking to your doctor.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

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